Lab Members

Anita Sil, Ph.D., M.D.

Principal Investigator

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Romina Abbasian

Assistant Specialist

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My study focuses on identifying the functional and biochemical characteristics of Histoplasma's virulence factors known as knottin proteins during macrophage infection

Nebat Ali

Graduate Student

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I'm interested in investigating the regulatory networks that govern virulence and morphology in Histoplasma capsulatum.

Anyce Godoy

Masters Student

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Leveraging tools originally developed for Histoplasma, I am investigating the molecular biology of morphological transition and virulence in the related fungal pathogen Paracoccidioides.

Sarah Heater

Graduate Student

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My research focuses on genome instability and how it relates to morphology, virulence, and gene expression in Histoplasma species.

Christina Homer, M.D., Ph.D.

Postdoctoral Fellow

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I am interested in understanding virulence factors in Coccidioides, the causative agent of Valley Fever, and how this pathogenic fungus interacts with host immune cells to cause serious disseminated infection in some human hosts.

Murat Can Kalem, Ph.D.

Postdoctoral Fellow

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I am exploring post-transcriptional mechanisms underlying temperature sensing and morphological transitions in thermally dimorphic fungi. I am hunting for eukaryotic RNA thermometers and temperature-dependent RNA binding protein functions while building a bridge between RNA biology and medical mycology.

Annette Mercedes

Junior Specialist

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I’m studying the role of a family of small-secreted effectors called knottins during Histoplasma capsulatum infections

Anna Morrison

Graduate Student

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I am investigating the effects of acute temperature shifts on the morphology and transcriptional profile of Histoplasma capsulatum.

Elena Ochoa

Staff Research Associate

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I am investigating how proteases affect the virulence and cell morphology of Coccidioides, the fungal respiratory pathogen that causes Valley Fever.

Rosa Rodriguez, Ph.D.

Specialist

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I'm studying how a family of small secreted effectors manipulate macrophages during Histoplasma infection.

Mark Roxas

Lab Assistant, Lab Manager

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I manage media and glassware.

Jane Symington, M.D., Ph.D.

Postdoctoral Fellow

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I am investigating the interactions between macrophages and Coccidioides, the cause of Coccidioidomycosis/Valley Fever.

Mark Voorhies, Ph.D.

Professional Researcher

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I provide bioinformatics support for the lab and maintain Histobase, a database of functional annotations for the Histoplasma genomes. I am interested in the evolution of temperature-dependent regulation of morphology in the Onygenales and in the parallel emergence of pathogenesis in these fungi.

Lab Alumni